The Interstate 10 in San Bernardino, abbreviated "i-10 San Bernardino", is the main interstate highway route that travels generally in a east-west direction across the metro LA area; traveling between the downtown LA area and the metro San Bernardino area. 

The i-10 in the San Bernardino area is also called/known as the "San Bernardino Freeway" or "San Berdo Freeway".

The map above shows the i-10 (highlighted in pink) where the i-10 travels between the metro San Bernardino area and the metro LA area... the map below shows the i-10 (highlighted in pink) where it travels through the San Bernardino area...